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VISQUE® InVivo Elite

VISQUE® inVivo Elite is a preclinical in vivo fluorescent & bioluminescent imaging and analysis system.

High Performance Cooling Camera

1) High Sensitivity Sensor

  • Pixel Pitch: 5.5 ㎛
  • Dynamic Range: 64 dB

2) Thermoelectric Cooling Technology

  • Cooling up to -20℃ below the ambient: unlike structures that use gas refrigerant to cool the system down, it does not require periodic replacement of refrigerant gas, making it easier to manage the system.

3) Multi-wavelength Fluorescence and Bioluminescence Imaging

  • Multi-wavelength: from visible to near-infrared wavelengths
  • Frame Rate: 24 fps
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Motorized Full HD Lens

1) Precise Control

  • Zoom with 9 Steps: 1x - 6x
  • Iris with 10 Steps: f/1.8 - close
  • Focus with 21 Steps: 0 cm - 10 cm

2) Various Field of View

  • Field of View: controls field of view from 5 cm x 4 cm to 28 cm x 21 cm
  • Imaging of More than 5 Mice

3) Real-time Imaging

  • Preview: views the interior of the darkroom in real-time to check the animals or control the zoom and focus of the lens precisely.
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Imaging of 5 mice at the same thime at 1.5x zoom(FOV:21cm x 16cm)

Advanced Emission Filter & Motorized Filter Wheel

1) Hard-coating Emission Filter

  • Minimization of Autofluorescence and Reflection
  • Blocking to a Level of OD 7

2) User-defined Filter Wheel

  • Up to 9 Emission Filters

3) Motorized Filter Wheel

  • Convenient Control with Dedicated Software, CleVue
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The previous version of the filter wheel

Special Design for Real-time Imaging

1) Faster Imaging

  • Double Doors: easy to take images when near infrared fluorescence imaging using the inner door.
  • Foot Switch: users can use both hands freely by stepping on the foot switch to start taking images.

2) Convenient Operation

  • Sliding Stage
  • Head Holder: minimizes animal movement using a head holder integrated with an anesthetic gas adapter (options for mouse and rat are available.)
  • Marker for Center Location of Imaging

3) Easy System Control

  • LCD Touch Screen: users can easily control external light, stage temperature, lens zoom, and imaging settings, etc.
  • Easy System Status Check
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Representative Detectable Dyes

Representative Detectable Dyes
Excitation / Emission Fluorescent Dyes
Ex: 390 - 490 ㎚
Em:500 - 550 ㎚
GFP / EGFP / Alexa488 / FITC /QD 525
Ex:530 - 570 ㎚
Em: 575 - 640 ㎚
RFP / DsRed / PE / Alexa 568 / TRITC / QD 585 / QD 605 / QD 625
Ex:620 - 650 ㎚
Em:690 - 740 ㎚
Ex:630 - 680 ㎚
Em:690 - 740 ㎚
Cy5.5 / PKE680 / Alexa 680 /Alexa 700 / QD 705
Ex: 740 - 790 ㎚
Em:810 - 860 ㎚
ICG / QD800

* User defined combinations of excitations and emissions are available.
These enables you to detect other fluorescent dyes that are not listed in the table above.

Technical Specifications arrow
Technical Specifications
VISQUE® InVivo Elite Note
Camera Sensor 4/3" CCD  
Device Operating Temperature 10 - 28℃  
Cooling To -10℃ Delta T = -20℃
Resolution (H x V) 1,600 x 1,200  
Minimum Image Pixel Resolution 33 ㎛ (at 6x)  
Frame rate Up to 24 frames/second  
FOV (H x V) 280 x 210 mm ~ 50 x 40 mm 10 steps, 6x motorized zooming lens
Maximum Exposure time 50 mins.  
Iris / focus Motorized Max. f/1.8
Filter Selection Automated  
Excitation Light LED light Blue, Green, Red, Far-rad, NIR, White
Emission Filters Max. 5 Filters Capacity Included 4 Filters
Filter Slots 6 positions  
Anestdesia Ventilator Adaptor Yes  
Dimension / Weight 56 x 56 x 90 cm, > 100 kg  
Applications Fluorescence, Bioluminescence,
Real-time imaging
Preview capture
 
Specialized Functions
Kinetics analysis Double (inner & outer) doors and
Y axis sliding stage system
Treatment, positioning and
imaging simultaneously
Stage Types 3-type stages
(5-mice / 1-mouse / 1-rat)
One stage is included in the device system
Heated stage Yes  (Off / 25℃ / 36℃)  
S/W 2 copies included Kinetics and Radiance analysis
LCD touch screen 7 inch LCD  

* Specifications are subject to change without prior notice.

* This system is only for research

  • image image
Citation Papers arrow
Title Publication (SCI) Link
A nanoscale photothermal agent based on a metal-organic coordination polymer as a drug-loading framework for effective combination therapy Acta Biomater. 2019 Aug;94:435-446 link
Blood flow characteristics of diabetic patients with complications detected by optical measurement BioMedical Engineering OnLine. 2018 17: 25 link
Age-related changes in pial arterial structure and blood flow in mice Neurobiol Aging. 2016 Jan;37:161-170 link
Exendin-4 protects hindlimb ischemic injury by inducing angiogenesis Biochem Biophys Res Commun. 2015 Oct 2;465(4):758-63. link
Use of indocyanine green for optical analysis of cortical infarcts in
photothrombotic ischemic brains
J Neurosci Methods. 2015 Jun 15;248:46-50 link
Optical measurement of mouse strain differences in cerebral
blood flow using indocyanine green
J Cereb Blood Flow Metab. 2015 Jun;35(6):912-6 link
Noninvasive Optical Measurement of Cerebral Blood
Flow in Mice Using Molecular Dynamics Analysis of
Indocyanine Green
PLoS One. 2012;7(10):e48383. link
Efficient differentiation of human pluripotent stem cells into
functional CD34 + progenitor cells by combined modulation of the
MEK/ERK and BMP4 signaling pathways
Blood. 2010 Dec 16;116(25):5762-72  link
Unsorted human adipose tissue-derived stem cells promote
angiogenesis and myogenesis in murine ischemic hindlimb model
Microvasc Res. 2010 Dec;80(3):310-6. link
Quantitative Analysis of Peripheral Tissue Perfusion
Using Spatiotemporal Molecular Dynamics
PLoS One. 2009;4(1):e4275. link

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