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CleVue

In vivo signal detection & intelligent image analysis
software for VISQUE®

Powerful Analysis

Advanced Kinetic Analysis

  • Patented algorithms for kinetic analysis of molecular diffusion phenomenon

    Tmax, Tarrival, Imax, Iarrival, Trising, 1st Peak, FluAngio, DyAngio, etc.

  • Kinetics visualization with feature maps
  • Time-series kinetics graphs

Spectrum Analysis

  • Spectral unmixing

    Clear multichannel fluorescence imaging

    Autofluorescence signals removal

  • Merge of multi-spectral images

ROI Analysis

  • Complete information of ROI

    Quantitative ROI information
    (statistics: min, max, mean, std dev, sum)

    Relative ROI information (ratio)

  • ROI selection

    Auto ROI (automatic selection of signals)

    Symmetric ROI (two-mirrored ROIs)

    Shaped ROI (rectangle, ellipse, polygon)

    Well plate ROI (6, 12, 24, 48, 96)

  • Copy and paste of ROIs among several images
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Unique Analysis Tools

CleVue Image File (CIF)

  • Exclusive file format for CleVue

    Including all information of an image
    (ROI values, acquisition settings, comments etc.)

    Making re-analysis easier

Advanced User Features

  • Various pseudo-coloring support
  • Unit conversion among intensity, radiance and radiance efficiency
  • Diverse filter options for image enhancement

    Median filter

    Round filter

  • User specific control of histogram

Multi-image Comparison

  • Up-to-4 image comparison at a time
  • Synchronization of window level and zoom/panning
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Specialized acquisition

Acquisition Setting

  • Preset according to the fluorescence dyes

    GFP, PE, Cy5.5, ICG, customized mode etc.

  • Combination of excitation and emission wavelengths
  • Differentiated acquisition type

    Accumulation, time-lapse

User Setting

  • Save and load of personalized acquisition setting
  • Sequential acquisitions for multi-spectral images

Convenient Workspace (Dual Windows)

  • Windows dedicated for acquisition and analysis
  • Support of multi-monitor environments
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Usability

Academic Writing Support

  • Report Mode: one-page summary of data

    Analyzed image, color scale bar, ROI values, acquisition information, comments etc.

  • Provision of various file formats

    Values (*.csv)

    Images (*.jpg, *.png, *.bmp, *.tif)

Image Loss Prevention

  • Auto saving of every acquired image

Intuitive User Interface

  • Front placement of frequently used icons
  • Customizable layout
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Citation Papers arrow
Title Journal (SCI) Link
A nanoscale photothermal agent based on a metal-organic coordination polymer as a drug-loading framework for effective combination therapy Acta Biomater. 2019 Aug;94:435-446 link
Blood flow characteristics of diabetic patients with complications detected by optical measurement BioMedical Engineering OnLine. 2018 17: 25 link
Age-related changes in pial arterial structure and blood flow in mice Neurobiol Aging. 2016 Jan;37:161-170 link
Exendin-4 protects hindlimb ischemic injury by inducing angiogenesis Biochem Biophys Res Commun. 2015 Oct 2;465(4):758-63. link
Use of indocyanine green for optical analysis of cortical infarcts in
photothrombotic ischemic brains
J Neurosci Methods. 2015 Jun 15;248:46-50 link
Optical measurement of mouse strain differences in cerebral
blood flow using indocyanine green
J Cereb Blood Flow Metab. 2015 Jun;35(6):912-6 link
Noninvasive Optical Measurement of Cerebral Blood
Flow in Mice Using Molecular Dynamics Analysis of
Indocyanine Green
PLoS One. 2012;7(10):e48383. link
Efficient differentiation of human pluripotent stem cells into
functional CD34 + progenitor cells by combined modulation of the
MEK/ERK and BMP4 signaling pathways
Blood. 2010 Dec 16;116(25):5762-72  link
Unsorted human adipose tissue-derived stem cells promote
angiogenesis and myogenesis in murine ischemic hindlimb model
Microvasc Res. 2010 Dec;80(3):310-6. link
Quantitative Analysis of Peripheral Tissue Perfusion
Using Spatiotemporal Molecular Dynamics
PLoS One. 2009;4(1):e4275. link
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