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VISQUE® InVivo ART

VISQUE® InVivo ART is a premium preclinical in vivo fluorescent & bioluminescent imaging and analysis system.

Superior Image Quality & Wide FOV

1) Advanced Cooling Technology

  • Camera cooling as low as -90℃
  • Adopts TEC technology with additional liquid chiller

2) Back-thinned CCD image sensor

  • Quantum Efficiency: Max. 94% @ 550 nm
  • Readout Noise: 7.0 e-@ 1MHz (ART 400) / 6.6 e-@ 1MH (ART 100 )

3) High-quality Image

  • High resolution image with 13.5 ㎛ (ART 400) / 13 ㎛ (ART 100) pixel size
  • Highly sensitive imaging from 400 - 900 ㎚



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Full HD Lens with Wider FOV

1) 10-mouse FOV

  • 27 x 27 cm Field of View (FOV): Sufficient for imaging 10 mice/rats at a time



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Applications

  • Small animal in vivo & ex vivo 2D optical imaging
  • Tracking tumor metastasis
  • Drug biodistribution & transporter targeting
  • Pharmacokinetic analysis
  • Vascular & lymphatic imaging
  • Optical imaging probe development

LED light source with specific wavelength

  • Employs up to 5 LEDs: Blue, Green, Red, HyperRed, N750
  • Concentrates on a specific wavelength range and can use light source energy



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High-performance Fluorescence Filters

1) Emission Filters

  • Up to 9 emission filters
  • Minimization of reflection

2) Excitation filter

  • 5 basic filters: 470, 550, 630, 650, 760 nm
  • Each filters are exchangeable to different filter (total of 16 filter options)

Intelligent in vivo Imaging Viewer & Kinetic Analysis Program

1) Fast and Convenient Analysis Tools

  • One-click analysis
    : automatic display of fluorescence level and simple setting
  • Image process
    : autofluorescence signal removal, merge of multi-spectral images
  • Report mode
    : the acquisition setup information, raw image, ROI, the range of pseudocolor bar, comments, etc.

2) Convenient Post-image Analysis and Edition Tools

  • *.cif analysis file output
  • The display and analysis of four-different images in one screen
  • Other supported formats
    : tif, bmp, jpg, png

3) Advanced Imaging and Analysis Software

  • Time-lapse imaging analysis
  • Kinetic analysis: Dynamics graph and 10 kinds of algorithms
  • Image analysis:
    Autofluorescence removal, Spectral unmixing, Merge of multi-spectral image
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Enhanced Usability with Refined Design & Optional Accessories

1) User-friendly Product Design

  • LED status window
  • Built-in touch sensor & Electromagnet for easier opening and closing the door
  • Interface panel: power switch, foot switch connector, Anesthesia ventilator adaptor outlet

2) Convenient Lens Control to Obtain Precise Imaging

  • Motorized Iris / Zoom / Focus for detailed adjustments
  • Real-time observation of inside of the equipment

3) Optional Accessories for Convenient Operation

  • Black mat
  • Foot switch
  • Anesthesia ventilator adaptor (availble for limited region)
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Representative Detectable Dyes

Representative Detectable Dyes
Excitation / Emission Fluorescent Dyes
Ex: 390 - 490 ㎚
Em:500 - 550 ㎚
GFP / EGFP / Alexa488 / FITC /QD 525
Ex:530 - 570 ㎚
Em: 575 - 640 ㎚
RFP / DsRed / PE / Alexa 568 / TRITC / QD 585 / QD 605 / QD 625
Ex:620 - 650 ㎚
Em:690 - 740 ㎚
Ex:630 - 680 ㎚
Em:690 - 740 ㎚
Cy5.5 / PKE680 / Alexa 680 /Alexa 700 / QD 705
Ex: 740 - 790 ㎚
Em:810 - 860 ㎚
ICG / QD800

* User defined combinations of excitations and emissions are available.
These enables you to detect other fluorescent dyes that are not listed in the table above.

Technical Specifications arrow
Technical Specifications
VISQUE® InVivo ART 400 VISQUE® InVivo ART 100
System
Imaging Capability in vivo Imaging, Bioluminescence, Fluorescence in vivo Imaging, Bioluminescence, Fluorescence  
Weight and Dimension 56 cm × 57 cm × 116 cm, 140 kg (308.6 lbs) 56 cm × 57 cm × 116 cm, 140 kg (308.6 lbs)  
Camera
Sensor 1.53” Backside Illuminated CCD 0.7” Backside Illuminated CCD
Cooling - 50℃ to -90℃ - 50℃ to -90℃  
Resolution (H X V) 2048 x 2048, 4 Mpixel 1024 × 1024, 1 Mpixel  
Pixel Size 13.5 ㎛ x 13.5 ㎛ 13 ㎛ x 13 ㎛
Digital Output 16 bit 16 bit
Binning 1 × 1, 2 × 2, 4 × 4 1 × 1, 2 × 2, 4 × 4
Fluorescence Filters
Light Source LED (5 kinds) LED (5 kinds)
Excitation Filter 5 filters, selectable from 16 kinds of filters 5 filters, selectable from 16 kinds of filters
Emission Filters Up to 9 filters (4 filters basically included) Up to 9 filters (4 filters basically included)
Lens
Control Motorized Iris / Zoom / Focus Motorized Iris / Zoom / Focus
Field of View (FOV) 27 cm × 27 cm - 10 cm × 10 cm 27 cm × 27 cm - 8 cm × 8 cm
Stage
Animal Capacity 10 mice / rat 10 mice / rat
Heating Stage Off / 25℃ / 36℃ Off / 25℃ / 36℃
Anesthesia Ventilator Adaptor Yes Yes
CleVue Software
Image Acquisition Mode Single-frame, Time-lapse imaging Single-frame, Time-lapse imaging
Supported File Format cif (exclusive file format), tif, bmp, jpg, png cif (exclusive file format), tif, bmp, jpg, png
Kinetic Analysis Dynamics graph and 10 kinds of algorithms for kinetic analysis Dynamics graph and 10 kinds of algorithms for kinetic analysis
Image Analysis Quantification, ROI, Autofluorescence removal,
Spectral unmixing, Merge of multi-spectral images
Quantification, ROI, Autofluorescence removal,
Spectral unmixing, Merge of multi-spectral images

* Specifications are subject to change without prior notice.

* This system is for research purpose only

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Citation Papers

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Documents User Manual
  • Korean
  • English
  • Chinese
English