topBtn

VISQUE® InVivo ART

VISQUE® InVivo ART is a premium preclinical in vivo fluorescent & bioluminescent imaging and analysis system.

Superior Image Quality & Wide FOV

1) Advanced Cooling Technology

  • Camera cooling as low as -80℃ (-90℃ with extra chiller unit)
  • Adopts TEC technology with additional liquid chiller

2) Back-thinned CCD image sensor

  • Quantum Efficiency: 90% @ 450 - 720 nm
  • Dark Current: 0.00013@-80℃ (ART 400), 0.00030@ -80℃ (ART 100)
  • Pixel well-depth: 100,000 e-

3) High-quality Image

  • High resolution image with 13.5 ㎛ (ART 400) / 13 ㎛ (ART 100) pixel size
  • Highly sensitive imaging from 350 - 950 ㎚



image

Full HD Lens with Wider FOV

1) 10-mouse FOV

  • 27 x 27 cm Field of View (FOV): Sufficient for imaging 10 mice/ 5 rats at a time



image

Applications

  • Small animal in vivo & ex vivo 2D optical imaging
  • Tracking tumor metastasis
  • Drug biodistribution & transporter targeting
  • Pharmacokinetic analysis
  • Vascular & lymphatic imaging
  • Optical imaging probe development

LED light source

  • Employs up to 5 LEDs: Blue, Green, Red, HyperRed, NIR
  • Strong light power due to concentrated light source energy on a specific wavelength
  • LED-based spectral unmixing
  • Immediate use (no warm-up/cool-down time)
  • Long lifespan (10,000 - 50,000 hours)
  • High SNR (signal to noise ratio) due to weak reflection (of excitation light) in the wavelength of emission filter in fluorescence imaing



image

High-performance Fluorescence Filters

1) Emission filters

  • Semrock filter: hard-coated filter width up to 6-7 optical density
  • Customizable filters (350- 950 nm)
  • Undesired reflection removed

2) Excitation filter

  • Semrock filter: hard-coated filter width up to 6-7 optical density
  • Customizable filters (440 - 770 nm)
image

Intelligent in vivo Imaging Viewer & Kinetic Analysis Program

1) Fast and Convenient Analysis Tools

  • One-click analysis
    : automatic display of fluorescence level and simple setting
  • Image process
    : autofluorescence signal removal, merge of multi-spectral images
  • Report mode
    : the acquisition setup information, raw image, ROI, the range of pseudocolor bar, comments, etc.

2) Convenient Post-image Analysis and Edition Tools

  • *.cif analysis file output
  • The display and analysis of four-different images in one screen
  • Other supported formats
    : tif, bmp, jpg, png

3) Advanced Imaging and Analysis Software

  • Time-lapse imaging analysis
  • Kinetic analysis: Dynamics graph and 10 kinds of algorithms
  • Image analysis:
    Autofluorescence removal, Spectral unmixing, Merge of multi-spectral image
image image

Enhanced Usability with Refined Design & Optional Accessories

1) User-friendly Product Design

  • LED status window
  • Built-in touch sensor & Electromagnet for easier opening and closing the door
  • Interface panel: power switch, foot switch connector, Anesthesia ventilator adaptor outlet

2) Convenient Lens Control to Obtain Precise Imaging

  • Convenient and detailed focus control with real-time observation of mice/rats
  • Motorized Iris / Zoom / Focus for detailed adjustments

3) Optional Accessories for Convenient Operation

  • Black mat
  • Foot switch
  • Anesthesia ventilator adaptor (availble for limited region)
image

Representative Detectable Dyes

Representative Detectable Dyes
Imaging – Mode Imaging - Light Excitation / Emission Fluorescent Dyes
GFP Blue Ex : 390 nm - 490 nm
Em : 500 nm - 550 nm
GFP / EGFP / Alexa 488 / FITC / QD 525
PE Green Ex : 530 nm - 570 nm
Em : 575 nm - 640 nm
RFP / DsRed / PE / Alexa 568 / TRITC / QD 585 / QD 605 / QD 625
Cy5.5 Red Ex : 620 nm - 650 nm
Em : 690 nm - 740 nm
Cy5.5 / PKE680 / Alexa 680 / Alexa 700 / QD 705
HyperRed Ex : 630 nm - 680 nm
Em : 690 nm - 740 nm
ICG NIR Ex : 740 nm - 790 nm
Em : 810 nm - 860 nm
ICG / QD 800

* User defined combinations of excitations and emissions are available.
These enables you to detect other fluorescent dyes that are not listed in the table above.

Technical Specifications arrow
Technical Specifications
VISQUE® InVivo ART 400 VISQUE® InVivo ART 100
System
Imaging Capability in vivo imaging, bioluminescence, fluorescence, time-lapse imaging in vivo imaging, bioluminescence, fluorescence, time-lapse imaging  
Weight and Dimension 56 cm × 57 cm × 116 cm, 140 kg (308.6 lbs) 56 cm × 57 cm × 116 cm, 140 kg (308.6 lbs)  
Camera
Sensor Size 1.53” 0.7”
Sensor Backside Illuminated CCD, Grade 1 Backside Illuminated CCD, Grade 1
Cooling -80℃ (-90℃ with extra chiller unit) -80℃ (-90℃ with extra chiller unit)  
Resolution (H X V) 2048 x 2048, 4 Mpixel 1024 × 1024, 1 Mpixel  
Pixel Size 13.5 ㎛ x 13.5 ㎛ 13 ㎛ x 13 ㎛
Digital Output 16 bit 16 bit
Binning 1 × 1, 2 × 2, 4 × 4, 8 x 8, 16 x 16 1 × 1, 2 × 2, 4 × 4, 8 x 8, 16 x 16
Fluorescence Filters
Light Source LED LED
Excitation Filter Customizable filter choices (350 - 950 nm) Customizable filter choices (350 - 950 nm)
Emission Filters Customizable filter choices (440 - 770 nm) Customizable filter choices (440 - 770 nm)
Lens
Control Motorized Iris / Zoom / Focus Motorized Iris / Zoom / Focus
Field of View (FOV) 27 cm × 27 cm - 10 cm × 10 cm 27 cm × 27 cm - 8 cm × 8 cm
Stage
Animal Capacity 10 mice / 3 rats 10 mice / 3 rats
Heating Stage Off / 25℃ / 36℃ Off / 25℃ / 36℃
Anesthesia Ventilator Adaptor Yes Yes
CleVue Software
Image Acquisition Mode Single-frame, Time-lapse imaging Single-frame, Time-lapse imaging
Supported File Format cif (exclusive file format), tif, bmp, jpg, png cif (exclusive file format), tif, bmp, jpg, png
Kinetic Analysis Dynamics graph and 10 kinds of algorithms for kinetic analysis Dynamics graph and 10 kinds of algorithms for kinetic analysis
Image Analysis Quantification, ROI, Autofluorescence removal,
Spectral unmixing, Merge of multi-spectral images
Quantification, ROI, Autofluorescence removal,
Spectral unmixing, Merge of multi-spectral images

* Specifications are subject to change without prior notice.

* This system is for research purpose only

  • image image
Citation Papers

Download

Documents Catalog
  • Korean
  • English
  • Chinese
English